Authorities closed the Anthony Wayne Trail near Detroit Avenue in Maumee, late Friday, after a rollover crash.
Both directions of the roadway were shut down as police investigated the collision that injured at least 2 people.
Dispatchers report that the accident may have been a head-on collision involving a drunk driver.
As of 11:50 p.m. on Friday it was unclear how seriously one driver, believed to have been driving on the wrong side of the road, was injured.
The other driver involved did not appear to suffer any life threatening injuries but was, in addition to the alleged wrong-way driver, also hospitalized.