Starting at 2 a.m. on Thursday, traffic between Queenswood and Kroger was being narrowed to one lane in each direction.
Crews are working to reconstruct Secor Road at the on and off ramps.
During the closure, the city suggests taking I-475 east to the ProMedica Parkway as an exit.
If you're headed west -- drivers can use Douglas Road, Monroe Street or Talmadge Road.
The portion of Secor that has been under construction will reopen all lanes to traffic.
View closures: ODOT Construction Info