The Ohio Department of Health says the baiting will continue through Sept. 20 and cover 4,334 square miles. The coated baits intended for raccoons are about the size of ketchup packets. They are white and rolled in a brown fishmeal glaze known to attract raccoons.
Baits will be distributed by aircraft and vehicles.
Five raccoon-rabies cases have been confirmed this year. The cases include four raccoons in Mahoning County and one cat in Trumbull County.
Rabies is a viral disease that affects people and animals and is almost always fatal.
Bats, raccoons and skunks pose the greatest risk of rabies in Ohio.