Toledo Police said the two-car crash happened before 6:30 a.m. on Dorr near Upton.
The drivers are said to have experienced minor injuries, but officials have said black ice on the roads contributed to the crash.
Crews are on scene clearing the roads as of this time.
Earlier Tuesday morning, a car crash was reported at High Level Bridge around 5:15 a.m. Officials said the car slipped on patches of ice. The driver was sent to the hospital with minor injuries.